21PA
Crystal structure of human MEK2 in complex with U0126
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Dual specificity mitogen-activated protein kinase kinase 2 | polymer | 345 | 38672.4 | 6 | UniProt (P36507) Pfam (PF00069) | Homo sapiens (human) | MAP kinase kinase 2,MAPKK 2,ERK activator kinase 2,MAPK/ERK kinase 2,MEK 2 |
| 2 | G, J, M, P, S... (A, B, C, D, E...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) PubChem (888) | |||
| 3 | H, K, N, Q, T... (A, B, C, D, E...) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 6 | Chemie (ANP) | |||
| 4 | I, L, O, R, U... (A, B, C, D, E...) | (2Z)-bis{amino[(2-aminophenyl)sulfanyl]methylidene}butanedinitrile | non-polymer | 380.5 | 6 | Chemie (5BM) PubChem (3006531) | |||
| 5 | AA, BA, CA, DA, Y... (C, D, E, F, A...) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 232034.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 5465.9 | |
| All* | Total formula weight | 237500.6 |
