21OJ
Crystal Structure of the second bromodomain of human BRD4 BD2 in complex with the covalent inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 4 | polymer | 113 | 13194.3 | 2 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (human) | Protein HUNK1 |
| 2 | C, E (A, B) | 4-[2-[2,6-dimethyl-4-[(2~{S})-2-methyl-3-oxidanyl-propoxy]phenoxy]-5-(2-oxidanylpropan-2-yl)phenyl]-6-methyl-7-oxidanylidene-~{N}-prop-2-ynyl-1~{H}-pyrrolo[2,3-c]pyridine-2-carboxamide | non-polymer | 571.7 | 2 | Chemie (A1E3W) | |||
| 3 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26388.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1235.4 | |
| All* | Total formula weight | 27624.0 |
