21MD
Cryo-EM structure of homotypic CENP-A nucleosome isolated from human cells
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3-like centromeric protein A | polymer | 162 | 18639.5 | 2 | UniProt (P49450) | Homo sapiens (human) | Centromere autoantigen A,Centromere protein A,CENP-A |
| 2 | B, F (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62805) | Homo sapiens (human) | |
| 3 | C, G (C, G) | Histone H2A type 1-B/E | polymer | 130 | 14165.6 | 2 | UniProt (P04908) | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 4 | D, H (D, H) | Histone H2B type 1-J | polymer | 126 | 13935.2 | 2 | UniProt (P06899) | Homo sapiens (human) | Histone H2B.1,Histone H2B.r,H2B/r |
| 5 | I, J (I, J) | DNA (131-MER) | polymer | 131 | 23547.6 | 2 | Homo sapiens |
Sequence modifications
A, E: 1 - 140 (UniProt: P49450)
| PDB | External Database | Details |
|---|---|---|
| Gly 141 | - | expression tag |
| Arg 142 | - | expression tag |
| Ile 143 | - | expression tag |
| Leu 144 | - | expression tag |
| Glu 145 | - | expression tag |
| Val 146 | - | expression tag |
| Leu 147 | - | expression tag |
| Phe 148 | - | expression tag |
| Gln 149 | - | expression tag |
| Gly 150 | - | expression tag |
| Pro 151 | - | expression tag |
| His 152 | - | expression tag |
| Met 153 | - | expression tag |
| Asp 154 | - | expression tag |
| Tyr 155 | - | expression tag |
| Lys 156 | - | expression tag |
| Asp 157 | - | expression tag |
| Asp 158 | - | expression tag |
| Asp 159 | - | expression tag |
| Asp 160 | - | expression tag |
| Lys 161 | - | expression tag |
| His 162 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 163364.7 | |
| All* | Total formula weight | 163364.7 |
