21FM

Crystal structure of human dUTPase in complex with dUMP

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (B, A, C)	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial	polymer	161	17586.8	3	UniProt (P33316)	Homo sapiens (human)	dUTPase,dUTP pyrophosphatase
2	D, E, F (B, A, C)	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	3	Chemie (UMP) PubChem (65063)
3	G, H, I (B, A, C)	water	water		18.0	285	Chemie (HOH)

Sequence modifications

B, A, C: 1 - 141 (UniProt: P33316)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	52760.3
Non-Polymers*	Number of molecules	3
	Total formula weight	924.5
All*	Total formula weight	53684.8

*Water molecules are not included.