21CB
Cryo-EM structure of DICER with pre-mir-517a-GU in pre-dicing state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Endoribonuclease Dicer | polymer | 1909 | 217989.0 | 1 | UniProt (Q9UPY3) Pfam (PF00270) Pfam (PF20930) Pfam (PF00271) Pfam (PF03368) Pfam (PF20931) Pfam (PF02170) Pfam (PF00636) Pfam (PF20932) | Homo sapiens (human) | Helicase with RNase motif,Helicase MOI |
| 2 | B (B) | RNA (58-MER) | polymer | 61 | 19621.6 | 1 | Homo sapiens |
Sequence modifications
A: 26 - 1922 (UniProt: Q9UPY3)
| PDB | External Database | Details |
|---|---|---|
| Met 14 | - | initiating methionine |
| Gly 15 | - | expression tag |
| His 16 | - | expression tag |
| His 17 | - | expression tag |
| His 18 | - | expression tag |
| His 19 | - | expression tag |
| His 20 | - | expression tag |
| His 21 | - | expression tag |
| His 22 | - | expression tag |
| His 23 | - | expression tag |
| His 24 | - | expression tag |
| His 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 237610.6 | |
| All* | Total formula weight | 237610.6 |
