21BO
CryoEM structure of H5N1 A/Texas/37/2024 HA bound to 3CF5 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, G (B, K, L) | The light chain of 3CF5 Fab | polymer | 214 | 23304.0 | 3 | Macaca mulatta | ||
| 2 | B, C, E (C, D, I) | Hemagglutinin | polymer | 552 | 62840.5 | 3 | UniProt (A0AAX6NN08) | Influenza A virus | |
| 3 | D, H, I (H, A, G) | The heavy chain of 3CF5 Fab | polymer | 232 | 24726.7 | 3 | Macaca mulatta | ||
| 4 | J, L, N (E, J, N) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 5 | K, M, O (F, M, O) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1405.3 | 3 | In PDB GlyTouCan (G85526ZL) | |||
| 6 | P, Q, R, S, T... (C, D, I) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 9 | Chemie (NAG) PubChem (24139) |
Sequence modifications
C, D, I: 1 - 504 (UniProt: A0AAX6NN08)
| PDB | External Database | Details |
|---|---|---|
| Ile 195 | Thr 211 | conflict |
| Ser 505 | - | expression tag |
| Gly 506 | - | expression tag |
| Arg 507 | - | expression tag |
| Glu 508 | - | expression tag |
| Asn 509 | - | expression tag |
| Leu 510 | - | expression tag |
| Tyr 511 | - | expression tag |
| Phe 512 | - | expression tag |
| Gln 513 | - | expression tag |
| Gly 514 | - | expression tag |
| Gly 515 | - | expression tag |
| Gly 516 | - | expression tag |
| Gly 517 | - | expression tag |
| Ser 518 | - | expression tag |
| Gly 519 | - | expression tag |
| Tyr 520 | - | expression tag |
| Ile 521 | - | expression tag |
| Pro 522 | - | expression tag |
| Glu 523 | - | expression tag |
| Ala 524 | - | expression tag |
| Pro 525 | - | expression tag |
| Arg 526 | - | expression tag |
| Asp 527 | - | expression tag |
| Gly 528 | - | expression tag |
| Gln 529 | - | expression tag |
| Ala 530 | - | expression tag |
| Tyr 531 | - | expression tag |
| Val 532 | - | expression tag |
| Arg 533 | - | expression tag |
| Lys 534 | - | expression tag |
| Asp 535 | - | expression tag |
| Gly 536 | - | expression tag |
| Glu 537 | - | expression tag |
| Trp 538 | - | expression tag |
| Val 539 | - | expression tag |
| Leu 540 | - | expression tag |
| Leu 541 | - | expression tag |
| Ser 542 | - | expression tag |
| Thr 543 | - | expression tag |
| Phe 544 | - | expression tag |
| Leu 545 | - | expression tag |
| Gly 546 | - | expression tag |
| His 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
| His 550 | - | expression tag |
| His 551 | - | expression tag |
| His 552 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 332613.5 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 5975.4 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1990.9 | |
| All* | Total formula weight | 340579.8 |
