21AV
Epitope and functional classification of human neutralizing antibodies against SFTSV Gn
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | BD70-4017 heavy chain | polymer | 125 | 13738.4 | 1 | Homo sapiens | ||
| 2 | B (D) | BD70-4017 light chain | polymer | 110 | 11427.6 | 1 | Homo sapiens | ||
| 3 | C (H) | Envelopment polyprotein | polymer | 321 | 35320.9 | 1 | UniProt (A0A7S9CEK0) | Severe fever with thrombocytopenia syndrome virus | M polyprotein |
| 4 | D (A) | BD70-4008 heavy chain | polymer | 123 | 13227.8 | 1 | Homo sapiens | ||
| 5 | E (B) | BD70-4008 light chain | polymer | 108 | 11541.7 | 1 | Homo sapiens | ||
| 6 | F, H (E, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 7 | G (F) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1235.1 | 1 | In PDB GlyTouCan (G55220VL) |
Sequence modifications
H: 20 - 340 (UniProt: A0A7S9CEK0)
| PDB | External Database | Details |
|---|---|---|
| Thr 321 | Met 321 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 85256.5 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 2083.9 | |
| All* | Total formula weight | 87340.4 |
