21AM

CryoEM structure of hGZMA-hGSDMBctd

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Granzyme A	polymer	243	26985.4	2	UniProt (P12544)	Homo sapiens (human)	CTL tryptase,Cytotoxic T-lymphocyte proteinase 1,Fragmentin-1,Granzyme-1,Hanukkah factor,H factor,HF
2	C, D (D, E)	Gasdermin-B	polymer	417	47497.9	2	UniProt (Q8TAX9)	Homo sapiens (human)	Gasdermin-like protein

Sequence modifications

A, B: 29 - 262 (UniProt: P12544)

PDB	External Database	Details
Ala 212	Ser 212	engineered mutation
Gly 263	-	expression tag
Lys 264	-	expression tag
Thr 265	-	expression tag
His 266	-	expression tag
His 267	-	expression tag
His 268	-	expression tag
His 269	-	expression tag
His 270	-	expression tag
His 271	-	expression tag

D, E: 1 - 416 (UniProt: Q8TAX9)

PDB	External Database	Details
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	148966.6
All*	Total formula weight	148966.6

*Water molecules are not included.