1ZZT
Bovine eNOS N368D/V106M double mutant with L-N(omega)-Nitroarginine-(4R)-Amino-L-Proline Amide Bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nitric-oxide synthase, endothelial | polymer | 416 | 46991.1 | 2 | UniProt (P29473) Pfam (PF02898) | Bos taurus (cattle) | EC-NOS, NOS, type III, NOSIII, Endothelial NOS, eNOS, Constitutive NOS, cNOS |
| 2 | C, H (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 3 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | E, I (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 5 | F, J (A, B) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
| 6 | G, K (A, B) | L-N(OMEGA)-NITROARGININE-(4R)-AMINO-L-PROLINE AMIDE | non-polymer | 330.3 | 2 | Chemie (DP9) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 372 | Chemie (HOH) |
Sequence modifications
A, B: 67 - 482 (UniProt: P29473)
| PDB | External Database | Details |
|---|---|---|
| Arg 100 | Cys 99 | see remark 999 |
| Met 106 | Val 105 | engineered mutation |
| Asp 368 | Asn 367 | engineered mutation |
| Cas 384 | Cys 383 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 93982.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2559.7 | |
| All* | Total formula weight | 96541.8 |
