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1ZYX

Crystal structure of the complex of a group IIA phospholipase A2 with a synthetic anti-inflammatory agent licofelone at 1.9A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Phospholipase A2 VRV-PL-VIIIapolymer12113629.81UniProt (P59071)
Pfam (PF00068)
Daboia russellii pulchellaPhosphatidylcholine 2- acylhydrolase, DPLA2
2B, C
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
3D
(A)
[6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-1H-PYRROLIZIN-5-YL]ACETIC ACIDnon-polymer379.91Chemie (LCF)
4E
(A)
waterwater18.0161Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight13629.8
Non-Polymers*Number of molecules3
Total formula weight572.0
All*Total formula weight14201.8
*Water molecules are not included.

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PDB entries from 2024-11-13

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