1ZXE
Crystal Structure of eIF2alpha Protein Kinase GCN2: D835N Inactivating Mutant in Apo Form
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Serine/threonine-protein kinase | polymer | 303 | 35564.5 | 6 | UniProt (P15442) Pfam (PF00069) In PDB | Saccharomyces cerevisiae (baker's yeast) | |
2 | A, B, C, D, E... | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
3 | water | water | 18.0 | 279 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 594 - 664 (UniProt: P15442)
A, B, C, D, E, F: 768 - 997 (UniProt: P15442)
PDB | External Database | Details |
---|---|---|
Ser 592 | - | cloning artifact |
Leu 593 | - | cloning artifact |
Mse 645 | Met 576 | modified residue |
PDB | External Database | Details |
---|---|---|
Mse 775 | Met 706 | modified residue |
Mse 788 | Met 719 | modified residue |
Asn 835 | Asp 766 | engineered mutation |
Mse 839 | Met 770 | modified residue |
Mse 889 | Met 820 | modified residue |
Mse 908 | Met 839 | modified residue |
Mse 918 | Met 849 | modified residue |
Mse 926 | Met 857 | modified residue |
Mse 951 | Met 882 | modified residue |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 213387.3 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 552.6 | |
All* | Total formula weight | 213939.8 |