1ZVM
Crystal structure of human CD38: cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ADP-ribosyl cyclase 1 | polymer | 256 | 29676.7 | 4 | UniProt (P28907) Pfam (PF02267) | Homo sapiens (human) | Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, Lymphocyte differentiation antigen CD38, T10, Acute lymphoblastic leukemia cells antigen CD38 |
| 2 | E, F, G, H, I... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 45 - 300 (UniProt: P28907)
| PDB | External Database | Details |
|---|---|---|
| Asp 100 | Asn 100 | engineered mutation |
| Ala 164 | Asn 164 | engineered mutation |
| Asp 209 | Asn 209 | engineered mutation |
| Asp 219 | Asn 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 118706.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 768.5 | |
| All* | Total formula weight | 119475.1 |
