1ZRK
Factor XI complexed with 3-hydroxypropyl 3-(7-amidinonaphthalene-1-carboxamido)benzenesulfonate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Coagulation factor XI | polymer | 238 | 26798.4 | 1 | UniProt (P03951) Pfam (PF00089) In PDB | Homo sapiens (human) | Plasma thromboplastin antecedent, PTA, FXI |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | A | 3-HYDROXYPROPYL 3-[({7-[AMINO(IMINO)METHYL]-1-NAPHTHYL}AMINO)CARBONYL]BENZENESULFONATE | non-polymer | 427.5 | 1 | Chemie (367) | |||
| 4 | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A: 16 - 245 (UniProt: P03951)
| PDB | External Database | Details |
|---|---|---|
| Ala 78 | Lys 455 | engineered mutation |
| Ser 123 | Cys 500 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26798.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 715.7 | |
| All* | Total formula weight | 27514.1 |
