1ZR0
Crystal Structure of Kunitz Domain 1 of Tissue Factor Pathway Inhibitor-2 with Bovine Trypsin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Cationic trypsin | polymer | 223 | 23310.3 | 2 | UniProt (P00760) Pfam (PF00089) | Bos taurus (cattle) | Beta-trypsin |
| 2 | B, D (B, D) | Tissue factor pathway inhibitor 2 | polymer | 63 | 7376.2 | 2 | UniProt (P48307) Pfam (PF00014) | Homo sapiens (human) | TFPI-2; Placental protein 5; PP5 |
| 3 | E, F (A, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 519 | Chemie (HOH) |
Sequence modifications
A, C: 16 - 245 (UniProt: P00760)
| PDB | External Database | Details |
|---|---|---|
| Thr 98 | Asp 165 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61373.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 80.2 | |
| All* | Total formula weight | 61453.2 |
