1ZI5
Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with H type I Trisaccharide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histo-blood group ABO system transferase (NAGAT) Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase | polymer | 293 | 34194.5 | 1 | UniProt (P16442) Pfam (PF03414) In PDB | Homo sapiens (human) | Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase (Histo-blood group A transferase) (A transferase) |
| 2 | B | alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 529.5 | 1 | In PDB BIRD (PRD_900049) GlyTouCan (G40696TO) | H type 1 antigen, beta anomer | ||
| 3 | A | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 4 | A | MERCURY (II) ION | non-polymer | 200.6 | 6 | Chemie (HG) | |||
| 5 | water | water | 18.0 | 213 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: P16442)
| PDB | External Database | Details |
|---|---|---|
| Phe 62 | - | cloning artifact |
| Met 63 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34194.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 529.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1607.7 | |
| All* | Total formula weight | 36331.7 |
