1ZI5
Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with H type I Trisaccharide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histo-blood group ABO system transferase (NAGAT) Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase | polymer | 293 | 34194.5 | 1 | UniProt (P16442) Pfam (PF03414) | Homo sapiens (human) | Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase (Histo-blood group A transferase) (A transferase) |
| 2 | B (B) | alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 529.5 | 1 | In PDB BIRD (PRD_900049) GlyTouCan (G40696TO) | H type 1 antigen, beta anomer | ||
| 3 | C (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) PubChem (1158) PubChem (93630083) PubChem (6031) PubChem (91746160) PubChem (6101632) PubChem (6604175) PubChem (3084486) PubChem (11811538) PubChem (12049241) PubChem (25323048) PubChem (44298965) PubChem (57448939) PubChem (53486216) PubChem (60098857) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (25323044) | |||
| 4 | D, E, F, G, H... (A) | MERCURY (II) ION | non-polymer | 200.6 | 6 | Chemie (HG) PubChem (26623) | |||
| 5 | J (A) | water | water | 18.0 | 213 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: P16442)
| PDB | External Database | Details |
|---|---|---|
| Phe 62 | - | cloning artifact |
| Met 63 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34194.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 529.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1607.7 | |
| All* | Total formula weight | 36331.7 |
