1ZGL
Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J | HLA class II histocompatibility antigen, DR alpha chain | polymer | 181 | 21084.8 | 4 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) In PDB | Homo sapiens (human) | MHC class II antigen DRA |
| 2 | B, E, H, K | major histocompatibility complex, class II, DR beta 5 | polymer | 192 | 22446.8 | 4 | UniProt (Q29787) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (Q30154) In PDB | Homo sapiens (human) | |
| 3 | C, F, I, L | Myelin basic protein | polymer | 15 | 1672.9 | 4 | UniProt (Q6AI64) UniProt (by SIFTS) (P02686) In PDB | Homo sapiens | MBP |
| 4 | M, Q, S, U | T cell receptor alpha chain | polymer | 209 | 22932.3 | 4 | UniProt (P01848) Pfam (PF09291) In PDB | Homo sapiens (human) | |
| 5 | P, R, T, V | T cell receptor beta chain | polymer | 249 | 27794.7 | 4 | UniProt (P01850) Pfam (PF07654) In PDB | Homo sapiens (human) |
Sequence modifications
C, F, I, L: 1 - 13 (UniProt: Q6AI64)
| PDB | External Database | Details |
|---|---|---|
| Gly 14 | - | cloning artifact |
| Gly 15 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 383726.3 | |
| All* | Total formula weight | 383726.3 |
