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1ZGF

carbonic anhydrase II in complex with trichloromethiazide as sulfonamide inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbonic anhydrase IIpolymer25929157.91UniProt (P00918)
Pfam (PF00194)
Homo sapiens (human)Carbonate dehydratase II, CA-II, Carbonic anhydrase C
2B, C
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
3D
(A)
6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDEnon-polymer380.71Chemie (TRU)
4E
(A)
(4-CARBOXYPHENYL)(CHLORO)MERCURYnon-polymer357.21Chemie (BE7)
5F
(A)
waterwater18.0173Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29157.9
Non-Polymers*Number of molecules4
Total formula weight868.6
All*Total formula weight30026.5
*Water molecules are not included.

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PDB entries from 2025-12-17

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