1ZBU
crystal structure of full-length 3'-exonuclease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 3'-5' exonuclease ERI1 | polymer | 349 | 40560.7 | 4 | UniProt (Q8IV48) Pfam (PF02037) Pfam (PF00929) | Homo sapiens (human) | Eri-1 homolog; Histone mRNA 3' end-specific exoribonuclease; Protein 3'hExo; HEXO |
| 2 | E, F, H, I, K... (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) PubChem (888) | |||
| 3 | G, J, M, P (A, B, C, D) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 4 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 349 (UniProt: Q8IV48)
| PDB | External Database | Details |
|---|---|---|
| Mse 1 | - | modified residue |
| Mse 79 | Met 78 | modified residue |
| Mse 116 | Met 115 | modified residue |
| Leu 213 | Trp 212 | conflict |
| Mse 214 | Met 213 | modified residue |
| Mse 235 | Met 234 | modified residue |
| Mse 280 | Met 279 | modified residue |
| Mse 286 | Met 285 | modified residue |
| Mse 309 | Met 308 | modified residue |
| Mse 322 | Met 321 | modified residue |
| Mse 328 | Met 327 | modified residue |
| Mse 344 | Met 343 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 162242.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1583.3 | |
| All* | Total formula weight | 163826.2 |






