1ZAF
Crystal structure of estrogen receptor beta complexed with 3-Bromo-6-hydroxy-2-(4-hydroxy-phenyl)-inden-1-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Estrogen receptor beta | polymer | 238 | 26907.0 | 2 | UniProt (Q92731) Pfam (PF00104) In PDB | Homo sapiens (human) | ER-beta |
| 2 | C, D | Nuclear receptor coactivator 1 | polymer | 13 | 1386.6 | 2 | UniProt (Q15788) In PDB | NCoA-1, Steroid receptor coactivator-1, SRC-1, RIP160, Hin-2 protein | |
| 3 | A, B | 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE | non-polymer | 317.1 | 2 | Chemie (789) | |||
| 4 | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence modifications
A, B: 263 - 500 (UniProt: Q92731)
C, D: 603 - 613 (UniProt: Q15788)
| PDB | External Database | Details |
|---|---|---|
| Ala 409 | Ser 409 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 601 | - | cloning artifact |
| Gly 602 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56587.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 634.3 | |
| All* | Total formula weight | 57221.4 |
