1Z8A
Human Aldose Reductase complexed with novel Sulfonyl-pyridazinone Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | aldose reductase | polymer | 316 | 35898.3 | 1 | GenBank (178489) Pfam (PF00248) UniProt (by SIFTS) (P15121) In PDB | Homo sapiens (human) | |
| 2 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | A | 6-[(5-CHLORO-3-METHYL-1-BENZOFURAN-2-YL)SULFONYL]PYRIDAZIN-3(2H)-ONE | non-polymer | 324.7 | 1 | Chemie (62P) | |||
| 4 | water | water | 18.0 | 375 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35898.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1068.1 | |
| All* | Total formula weight | 36966.5 |
