1Z5O
Crystal structure of MTA/AdoHcy nucleosidase Asp197Asn mutant complexed with 5'-methylthioadenosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | MTA/SAH nucleosidase | polymer | 242 | 25487.1 | 2 | UniProt (P24247) Pfam (PF01048) UniProt (by SIFTS) (P0AF12) | Escherichia coli | P46; 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase |
| 2 | C, D (A, B) | 5'-DEOXY-5'-METHYLTHIOADENOSINE | non-polymer | 297.3 | 2 | Chemie (MTA) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 270 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 232 (UniProt: P24247)
| PDB | External Database | Details |
|---|---|---|
| Phe -10 | - | cloning artifact |
| Gln -9 | - | cloning artifact |
| Gly -8 | - | cloning artifact |
| Ala -7 | - | cloning artifact |
| Met -6 | - | cloning artifact |
| Asp -5 | - | cloning artifact |
| Pro -4 | - | cloning artifact |
| Glu -3 | - | cloning artifact |
| Phe -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| Asn 197 | Asp 197 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50974.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 594.7 | |
| All* | Total formula weight | 51568.9 |
