1Z4I
Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with deoxyribouridine 5'-monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5'(3')-deoxyribonucleotidase | polymer | 197 | 22840.1 | 1 | UniProt (Q9NPB1) Pfam (PF06941) | Homo sapiens (human) | Mitochondrial deoxyribonucleotidase, 5',3'-nucleotidase, mitochondrial, Deoxy-5'-nucleotidase 2, dNT-2 |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 1 | Chemie (UMP) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
A: 32 - 228 (UniProt: Q9NPB1)
| PDB | External Database | Details |
|---|---|---|
| Asn 41 | Asp 41 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22840.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 424.6 | |
| All* | Total formula weight | 23264.7 |
