1Z3U
Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in Tie2 Recognition
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Angiopoietin-2 | polymer | 217 | 24597.4 | 4 | UniProt (O15123) Pfam (PF00147) In PDB | Homo sapiens (human) | ANG-2 |
2 | A, B, C, D | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
3 | water | water | 18.0 | 379 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 281 - 496 (UniProt: O15123)
PDB | External Database | Details |
---|---|---|
Ser 280 | - | cloning artifact |
Ala 469 | Phe 469 | engineered mutation |
Ala 475 | Tyr 475 | engineered mutation |
Ala 476 | Tyr 476 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 98389.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 160.3 | |
All* | Total formula weight | 98549.8 |