1Z3U
Structure of the Angiopoietin-2 Recptor Binding Domain and Identification of Surfaces Involved in Tie2 Recognition
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Angiopoietin-2 | polymer | 217 | 24597.4 | 4 | UniProt (O15123) Pfam (PF00147) | Homo sapiens (human) | ANG-2 |
| 2 | E, F, G, H (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 379 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 281 - 496 (UniProt: O15123)
| PDB | External Database | Details |
|---|---|---|
| Ser 280 | - | cloning artifact |
| Ala 469 | Phe 469 | engineered mutation |
| Ala 475 | Tyr 475 | engineered mutation |
| Ala 476 | Tyr 476 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 98389.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 98549.8 |
