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1Z1R

HIV-1 protease complexed with Macrocyclic peptidomimetic inhibitor 2

Replaces:  1B6O
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BPol polyproteinpolymer9910765.72UniProt (P03369)
Pfam (PF00077)
In PDB
2A, BSULFATE IONnon-polymer96.13Chemie (SO4)
3A2-[(8S,11S)-11-{(1R)-1-HYDROXY-2-[ISOPENTYL(PHENYLSULFONYL)AMINO]ETHYL}-6,9-DIOXO-2-OXA-7,10-DIAZABICYCLO[11.2.2]HEPTADECA-1(15),13,16-TRIEN-8-YL]ACETAMIDEnon-polymer588.71Chemie (HBH)
4waterwater18.0102Chemie (HOH)
Sequence modifications
A, B: 1 - 99 (UniProt: P03369)
PDBExternal DatabaseDetails
Lys 7Gln 63engineered mutation
Ile 33Leu 89engineered mutation
Aba 67Cys 123engineered mutation
Aba 95Cys 151engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight21531.4
Non-Polymers*Number of molecules4
Total formula weight876.9
All*Total formula weight22408.3
*Water molecules are not included.

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PDB entries from 2024-04-24

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