1Z0J
Structure of GTP-Bound Rab22Q64L GTPase in complex with the minimal Rab binding domain of Rabenosyn-5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ras-related protein Rab-22A | polymer | 170 | 19182.9 | 1 | UniProt (P35285) Pfam (PF00071) | Mus musculus (house mouse) | Rab-22 |
| 2 | B (B) | FYVE-finger-containing Rab5 effector protein rabenosyn-5 | polymer | 59 | 6675.4 | 1 | GenBank (11641241) Pfam (PF11464) UniProt (by SIFTS) (Q9H1K0) | Homo sapiens (human) | |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 5 | E (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 6 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | G, H (A, B) | water | water | 18.0 | 301 | Chemie (HOH) |
Sequence modifications
A: 2 - 169 (UniProt: P35285)
B: 728 - 784 (GenBank: 11641241)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | cloning artifact |
| Ser 1 | - | cloning artifact |
| Met 22 | Val 22 | SEE REMARK 999 |
| Leu 64 | Gln 64 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 726 | - | cloning artifact |
| Ser 727 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25858.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 761.7 | |
| All* | Total formula weight | 26620.1 |
