1YYH

Crystal structure of the human Notch 1 ankyrin domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Notch 1, ankyrin domain	polymer	253	27778.8	2	UniProt (P46531) Pfam (PF00023) Pfam (PF12796)	Homo sapiens (human)	Neurogenic locus notch homolog protein 1; hN1; Translocation-associated notch protein TAN-1
2	C, D (A, B)	water	water		18.0	537	Chemie (HOH)

Sequence modifications

A, B: 1 - 243 (UniProt: P46531)

PDB	External Database	Details
Leu 244	-	expression tag
Glu 245	-	expression tag
His 246	-	expression tag
His 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55557.7
All*	Total formula weight	55557.7

*Water molecules are not included.