1YXS

Crystal Structure of Kinase Pim1 with P123M mutation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Proto-oncogene serine/threonine-protein kinase Pim-1	polymer	293	33866.4	1	UniProt (P11309) Pfam (PF00069) In PDB	Homo sapiens (human)
2	A	IMIDAZOLE	non-polymer		69.1	1	Chemie (IMD)
3		water	water		18.0	174	Chemie (HOH)

Sequence modifications

A: 29 - 313 (UniProt: P11309)

PDB	External Database	Details
Met 123	Pro 123	engineered mutation
Val 314	-	expression tag
Asp 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33866.4
Non-Polymers*	Number of molecules	1
	Total formula weight	69.1
All*	Total formula weight	33935.5

*Water molecules are not included.