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1YWT

Crystal structure of the human sigma isoform of 14-3-3 in complex with a mode-1 phosphopeptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
14-3-3 protein sigmapolymer24827807.12UniProt (P31947)
Pfam (PF00244)
Homo sapiens (human)Stratifin, Epithelial cell marker protein 1
2C, D
(C, D)
synthetic optimal phosphopeptide (mode-1)polymer121416.52
3E
(B)
CALCIUM IONnon-polymer40.11Chemie (CA)
4F, G, H
(A, B, D)
waterwater18.055Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight58447.2
Non-Polymers*Number of molecules1
Total formula weight40.1
All*Total formula weight58487.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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