1YVQ
The low salt (PEG) crystal structure of CO Hemoglobin E (betaE26K) approaching physiological pH (pH 7.5)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Hemoglobin alpha chain | polymer | 141 | 15150.4 | 2 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (human) | |
| 2 | B, D (B, D) | Hemoglobin beta chain | polymer | 146 | 15890.3 | 2 | UniProt (P68871) Pfam (PF00042) | Homo sapiens (human) | |
| 3 | E, G, I, K (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 4 | F, H, J, L (A, B, C, D) | CARBON MONOXIDE | non-polymer | 28.0 | 4 | Chemie (CMO) | |||
| 5 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 592 | Chemie (HOH) |
Sequence modifications
B, D: 1 - 146 (UniProt: P68871)
| PDB | External Database | Details |
|---|---|---|
| Lys 26 | Glu 26 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62081.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2578.0 | |
| All* | Total formula weight | 64659.2 |
