1YV3
The structural basis of blebbistatin inhibition and specificity for myosin II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Myosin II heavy chain | polymer | 762 | 86747.1 | 1 | UniProt (P08799) Pfam (PF02736) Pfam (PF00063) | Dictyostelium discoideum | |
| 2 | B, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | C (A) | VANADATE ION | non-polymer | 114.9 | 1 | Chemie (VO4) | |||
| 4 | E (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | F (A) | (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE | non-polymer | 292.3 | 1 | Chemie (BIT) | |||
| 6 | G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | H (A) | water | water | 18.0 | 678 | Chemie (HOH) |
Sequence modifications
A: 1 - 762 (UniProt: P08799)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | Met 1 | see remark 999 |
| Ser 249 | Asn 249 | see remark 999 |
| Cys 312 | Tyr 312 | see remark 999 |
| Leu 760 | Gln 760 | see remark 999 |
| Pro 761 | Arg 761 | see remark 999 |
| Asn 762 | Ile 762 | see remark 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 86747.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 945.1 | |
| All* | Total formula weight | 87692.3 |
