1YV3
The structural basis of blebbistatin inhibition and specificity for myosin II
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Myosin II heavy chain | polymer | 762 | 86747.1 | 1 | UniProt (P08799) Pfam (PF02736) Pfam (PF00063) In PDB | Dictyostelium discoideum | |
2 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
3 | A | VANADATE ION | non-polymer | 114.9 | 1 | Chemie (VO4) | |||
4 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
5 | A | (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE | non-polymer | 292.3 | 1 | Chemie (BIT) | |||
6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
7 | water | water | 18.0 | 678 | Chemie (HOH) |
Sequence modifications
A: 1 - 762 (UniProt: P08799)
PDB | External Database | Details |
---|---|---|
Gly 1 | Met 1 | see remark 999 |
Ser 249 | Asn 249 | see remark 999 |
Cys 312 | Tyr 312 | see remark 999 |
Leu 760 | Gln 760 | see remark 999 |
Pro 761 | Arg 761 | see remark 999 |
Asn 762 | Ile 762 | see remark 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 86747.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 945.1 | |
All* | Total formula weight | 87692.3 |