1YT7
Cathepsin K complexed with a constrained ketoamide inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cathepsin K | polymer | 215 | 23523.5 | 1 | UniProt (P43235) Pfam (PF00112) In PDB | Homo sapiens (human) | Cathepsin O, Cathepsin X, Cathepsin O2 |
2 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
3 | A | (1R)-2,2-DIMETHYL-1-({5-[4-(TRIFLUOROMETHYL)PHENYL]-1,3,4-OXADIAZOL-2-YL}METHYL)PROPYL (1S)-1-{OXO[(2-OXO-1,3-OXAZOLIDIN-3-YL)AMINO]ACETYL}PENTYLCARBAMATE | non-polymer | 583.6 | 1 | Chemie (3FC) | |||
4 | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23523.5 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 775.7 | |
All* | Total formula weight | 24299.2 |