1YSZ
Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL SOAKED WITH NECA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Endoplasmin | polymer | 236 | 26514.0 | 1 | UniProt (P41148) Pfam (PF13589) | Canis lupus familiaris (dog) | 94 kDa glucose-regulated protein, GRP94 |
| 2 | B (A) | N-ETHYL-5'-CARBOXAMIDO ADENOSINE | non-polymer | 308.3 | 1 | Chemie (NEC) PubChem (104795) PubChem (23913416) PubChem (24867503) PubChem (40967901) PubChem (40967902) PubChem (44308232) PubChem (44338050) PubChem (686179) PubChem (50987963) PubChem (1254895) PubChem (5342881) PubChem (2868392) PubChem (6541320) PubChem (6603839) PubChem (6604901) PubChem (6610317) PubChem (7068779) PubChem (7256363) PubChem (7256365) PubChem (448222) PubChem (11957539) PubChem (118705485) PubChem (124720172) PubChem (133688337) PubChem (138106599) | |||
| 3 | C, D, E (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) PubChem (8200) | |||
| 4 | F (A) | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence modifications
A: 69 - 286 (UniProt: P41148)
A: 328 - 337 (UniProt: P41148)
| PDB | External Database | Details |
|---|---|---|
| Gly 65 | - | cloning artifact |
| Ser 66 | - | cloning artifact |
| His 67 | - | cloning artifact |
| Met 68 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 324 | - | SEE REMARK 999 |
| Gly 325 | - | SEE REMARK 999 |
| Gly 326 | - | SEE REMARK 999 |
| Gly 327 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26514.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 891.0 | |
| All* | Total formula weight | 27405.0 |
