1YSI
Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Apoptosis regulator Bcl-X | polymer | 181 | 20804.9 | 1 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | Homo sapiens (human) | Bcl-2-like 1 protein |
2 | A | N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITRO-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE | non-polymer | 551.6 | 1 | Chemie (N3B) |
Sequence modifications
A: 5 - 48 (UniProt: Q07817)
A: 89 - 213 (UniProt: Q07817)
PDB | External Database | Details |
---|---|---|
Met 1 | - | expression tag |
Ser 2 | - | expression tag |
Met 3 | - | expression tag |
Ala 4 | - | expression tag |
Leu 214 | - | expression tag |
Glu 215 | - | expression tag |
His 216 | - | expression tag |
His 217 | - | expression tag |
His 218 | - | expression tag |
His 219 | - | expression tag |
His 220 | - | expression tag |
PDB | External Database | Details |
---|---|---|
His 181 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 20804.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 551.6 | |
All* | Total formula weight | 21356.5 |