1YSG
Solution Structure of the Anti-apoptotic Protein Bcl-xL in Complex with "SAR by NMR" Ligands
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Apoptosis regulator Bcl-X | polymer | 181 | 20804.9 | 1 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | Homo sapiens (human) | Bcl-2-like 1 protein |
| 2 | A | 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID | non-polymer | 216.2 | 1 | Chemie (4FC) | |||
| 3 | A | 5,6,7,8-TETRAHYDRONAPHTHALEN-1-OL | non-polymer | 148.2 | 1 | Chemie (TN1) |
Sequence modifications
A: 5 - 48 (UniProt: Q07817)
A: 89 - 213 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| Met 3 | - | cloning artifact |
| Ala 4 | - | cloning artifact |
| Leu 214 | - | cloning artifact |
| Glu 215 | - | cloning artifact |
| His 216 | - | cloning artifact |
| His 217 | - | cloning artifact |
| His 218 | - | cloning artifact |
| His 219 | - | cloning artifact |
| His 220 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| His 181 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20804.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 364.4 | |
| All* | Total formula weight | 21169.3 |
