1YP7

Van der Waals Interactions Dominate Hydrophobic Association in a Protein Binding Site Occluded From Solvent Water

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	MAJOR URINARY PROTEIN 1	polymer	174	20123.4	1	UniProt (P11588) Pfam (PF00061) In PDB	Mus musculus (house mouse)	MUP 1
2	A	CADMIUM ION	non-polymer		112.4	3	Chemie (CD)
3		water	water		18.0	176	Chemie (HOH)

Sequence modifications

A: 1 - 162 (UniProt: P11588)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Lys 50	Asn 68	engineered mutation
Phe 120	Tyr 138	engineered mutation
Glu 140	Lys 158	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	20123.4
Non-Polymers*	Number of molecules	3
	Total formula weight	337.2
All*	Total formula weight	20460.6

*Water molecules are not included.