1YOK
crystal structure of human LRH-1 bound with TIF-2 peptide and phosphatidylglycerol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Orphan nuclear receptor NR5A2 | polymer | 256 | 29800.5 | 1 | UniProt (O00482) Pfam (PF00104) | Homo sapiens (human) | Alpha-1-fetoprotein transcription factor, Hepatocytic transcription factor, B1-binding factor, hB1F, CYP7A promoter binding factor |
| 2 | B, C (B, C) | Nuclear receptor coactivator 2 | polymer | 14 | 1708.9 | 2 | UniProt (Q15596) | NCoA-2, Transcriptional intermediary factor 2 | |
| 3 | D (A) | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE | non-polymer | 747.0 | 1 | Chemie (P6L) | |||
| 4 | E, F, G (A, B, C) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence modifications
A: 300 - 541 (UniProt: O00482)
| PDB | External Database | Details |
|---|---|---|
| Met 286 | - | cloning artifact |
| Lys 287 | - | cloning artifact |
| Lys 288 | - | cloning artifact |
| His 289 | - | cloning artifact |
| His 290 | - | cloning artifact |
| His 291 | - | cloning artifact |
| His 292 | - | cloning artifact |
| His 293 | - | cloning artifact |
| His 294 | - | cloning artifact |
| Leu 295 | - | cloning artifact |
| Val 296 | - | cloning artifact |
| Pro 297 | - | cloning artifact |
| Arg 298 | - | cloning artifact |
| Gly 299 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 33218.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 747.0 | |
| All* | Total formula weight | 33965.4 |
