1YJD
Crystal structure of human CD28 in complex with the Fab fragment of a mitogenic antibody (5.11A1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Fab fragment of 5.11A1 antibody light chain | polymer | 212 | 23388.8 | 1 | Mus musculus (house mouse) | ||
| 2 | B (H) | Fab fragment of 5.11A1 antibody heavy chain | polymer | 222 | 24108.9 | 1 | Mus musculus (house mouse) | ||
| 3 | C (C) | T-cell-specific surface glycoprotein CD28 | polymer | 140 | 15784.1 | 1 | UniProt (P10747) Pfam (PF15910) | Homo sapiens (human) | TP44 |
| 4 | D, E, F (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 5 | G, H, I (L, H, C) | water | water | 18.0 | 203 | Chemie (HOH) |
Sequence modifications
C: -1 - 134 (UniProt: P10747)
| PDB | External Database | Details |
|---|---|---|
| Leu 135 | - | cloning artifact |
| Val 136 | - | cloning artifact |
| Pro 137 | - | cloning artifact |
| Arg 138 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 63281.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 63945.5 |
