1YHV
Crystal Structure of PAK1 kinase domain with two point mutations (K299R, T423E)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase PAK 1 | polymer | 297 | 33301.2 | 1 | UniProt (Q13153) Pfam (PF00069) In PDB | Homo sapiens (human) | p21-activated kinase 1; PAK-1; P65-PAK; Alpha-PAK |
| 2 | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A: 249 - 545 (UniProt: Q13153)
| PDB | External Database | Details |
|---|---|---|
| Arg 299 | Lys 299 | engineered mutation |
| Glu 423 | Thr 423 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33301.2 | |
| All* | Total formula weight | 33301.2 |
