1YHS
Crystal structure of Pim-1 bound to staurosporine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene serine/threonine-protein kinase Pim-1 | polymer | 273 | 31673.9 | 1 | UniProt (P11309) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | B (A) | STAUROSPORINE | non-polymer | 466.5 | 1 | Chemie (STU) PubChem (5279) PubChem (71203703) PubChem (42610657) PubChem (44259) PubChem (44299148) PubChem (49831000) PubChem (25322871) PubChem (28684983) PubChem (44120114) PubChem (44537813) PubChem (46864193) PubChem (68262703) PubChem (68306294) PubChem (451705) PubChem (73953205) PubChem (86306248) PubChem (358479) PubChem (5280487) PubChem (5459111) PubChem (5311103) PubChem (6711321) PubChem (9956178) PubChem (6419748) PubChem (9804568) PubChem (122130844) PubChem (12046017) PubChem (9937179) PubChem (143163481) PubChem (143224059) PubChem (143494026) PubChem (162978898) | |||
| 3 | C (A) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
A: 33 - 305 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Cme 161 | Cys 161 | modified residue |
| Sep 261 | Ser 261 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31673.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 466.5 | |
| All* | Total formula weight | 32140.4 |
