1YDL
Crystal Structure of the Human TFIIH, Northeast Structural Genomics Target HR2045.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | general transcription factor IIH, polypeptide 5 | polymer | 79 | 9234.1 | 1 | UniProt (Q6ZYL4) Pfam (PF06331) | Homo sapiens (human) | TFIIH |
| 2 | B (A) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A: -7 - 71 (UniProt: Q6ZYL4)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | cloning artifact |
| His -5 | - | cloning artifact |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 1 | Met | SEE REMARK 999 |
| His 2 | Val 2 | SEE REMARK 999 |
| Gly 3 | Asn 3 | SEE REMARK 999 |
| Thr 4 | Val 4 | SEE REMARK 999 |
| Arg 5 | Leu 5 | SEE REMARK 999 |
| Mse 8 | Val 8 | engineered mutation |
| Mse 16 | Met 16 | modified residue |
| Mse 61 | Met 61 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 9234.1 | |
| All* | Total formula weight | 9234.1 |
