1YDK
Crystal structure of the I219A mutant of human glutathione transferase A1-1 with S-hexylglutathione
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Glutathione S-transferase A1 | polymer | 222 | 25628.0 | 2 | UniProt (P08263) Pfam (PF02798) Pfam (PF00043) In PDB | Homo sapiens (human) | GTH1, HA subunit 1, GST- epsilon, GSTA1-1, GST class-alpha |
2 | A, B | S-HEXYLGLUTATHIONE | non-polymer | 392.5 | 2 | Chemie (GTX) | |||
3 | water | water | 18.0 | 409 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 222 (UniProt: P08263)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Ala 219 | Ile 218 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 51256.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 785.0 | |
All* | Total formula weight | 52041.1 |