1Y8O
Crystal structure of the PDK3-L2 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 | polymer | 419 | 48291.0 | 1 | UniProt (Q15120) Pfam (PF10436) Pfam (PF02518) In PDB | Homo sapiens (human) | Pyruvate dehydrogenase kinase isoform 3 |
2 | B | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | polymer | 128 | 14192.1 | 1 | UniProt (P10515) Pfam (PF00364) In PDB | Homo sapiens (human) | E2, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, PDC-E2, 70 kDa mitochondrial autoantigen of primary biliary cirrhosis, PBC, M2 antigen complex 70 kDa subunit |
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | A | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
5 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
6 | B | DIHYDROLIPOIC ACID | non-polymer | 208.3 | 1 | Chemie (RED) | |||
7 | water | water | 18.0 | 67 | Chemie (HOH) |
Sequence modifications
A: 9 - 406 (UniProt: Q15120)
B: 126 - 233 (UniProt: P10515)
PDB | External Database | Details |
---|---|---|
Gly -12 | - | cloning artifact |
Gly -11 | - | cloning artifact |
Ser -10 | - | cloning artifact |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
Gly -3 | - | cloning artifact |
Met -2 | - | cloning artifact |
Ala -1 | - | cloning artifact |
Arg 0 | - | cloning artifact |
Leu 1 | - | cloning artifact |
Glu 2 | - | cloning artifact |
Asn 3 | - | cloning artifact |
Leu 4 | - | cloning artifact |
Tyr 5 | - | cloning artifact |
Phe 6 | - | cloning artifact |
Gln 7 | - | cloning artifact |
Gly 8 | - | cloning artifact |
PDB | External Database | Details |
---|---|---|
Gly 106 | - | cloning artifact |
Gly 107 | - | cloning artifact |
Ser 108 | - | cloning artifact |
His 109 | - | expression tag |
His 110 | - | expression tag |
His 111 | - | expression tag |
His 112 | - | expression tag |
His 113 | - | expression tag |
His 114 | - | expression tag |
Gly 115 | - | cloning artifact |
Met 116 | - | cloning artifact |
Ala 117 | - | cloning artifact |
Arg 118 | - | cloning artifact |
Leu 119 | - | cloning artifact |
Glu 120 | - | cloning artifact |
Asn 121 | - | cloning artifact |
Leu 122 | - | cloning artifact |
Tyr 123 | - | cloning artifact |
Phe 124 | - | cloning artifact |
Gln 125 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 62483.1 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 738.0 | |
All* | Total formula weight | 63221.1 |