1Y6P
Crystal structure of disulfide engineered porcine pancratic phospholipase a2 to group-x isozyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phospholipase A2, major isoenzyme | polymer | 131 | 14712.5 | 2 | UniProt (P00592) Pfam (PF00068) | Sus scrofa (pig) | Phosphatidylcholine 2-acylhydrolase, Group IB phospholipase A2 |
| 2 | C, D, F (A, B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 3 | E, G (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 216 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 124 (UniProt: P00592)
| PDB | External Database | Details |
|---|---|---|
| Leu 8 | Met 30 | engineered mutation |
| Leu 20 | Met 42 | engineered mutation |
| Cys 50 | Asn 72 | engineered mutation |
| Lys 125 | - | SEE REMARK 999 |
| Gly 126 | - | SEE REMARK 999 |
| Glu 127 | - | SEE REMARK 999 |
| Ser 128 | - | SEE REMARK 999 |
| Asp 129 | - | SEE REMARK 999 |
| Lys 130 | - | SEE REMARK 999 |
| Cys 131 | - | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29425.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 191.1 | |
| All* | Total formula weight | 29616.2 |
