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1Y6A

Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Vascular endothelial growth factor receptor 2polymer36641676.71UniProt (P35968)
Pfam (PF07714)
Homo sapiens (human)VEGFR-2, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1
2B
(A)
N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINEnon-polymer435.51Chemie (AAZ)
3C
(A)
waterwater18.0150Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41676.7
Non-Polymers*Number of molecules1
Total formula weight435.5
All*Total formula weight42112.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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