1Y5U
Dianhydrosugar-based benzamidine, factor Xa specific inhibitor in complex with bovine trypsin mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | T | Trypsin, cationic | polymer | 223 | 23389.3 | 1 | UniProt (P00760) Pfam (PF00089) In PDB | Bos taurus (bovine) | Beta-trypsin |
2 | T | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
3 | T | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | T | 2-O-{3-[AMINO(IMINO)METHYL]PHENYL}-5-O-{4-[AMINO(IMINO)METHYL]PHENYL}-1,4:3,6-DIANHYDRO-D-GLUCITOL | non-polymer | 382.4 | 1 | Chemie (TL4) | |||
5 | T | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
6 | T | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
7 | T | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
8 | water | water | 18.0 | 227 | Chemie (HOH) |
Sequence modifications
T: 16 - 245 (UniProt: P00760)
PDB | External Database | Details |
---|---|---|
Glu 97 | Asn 99 | engineered mutation |
Tyr 99 | Leu 101 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23389.3 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 881.9 | |
All* | Total formula weight | 24271.2 |