1Y4J

Crystal structure of the paralogue of the human formylglycine generating enzyme

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Sulfatase modifying factor 2	polymer	284	32274.9	2	UniProt (Q8NBJ7) Pfam (PF03781)	Homo sapiens (human)	C-alpha-formyglycine- generating enzyme 2, UNQ1968/PRO4500
2	C (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	1	In PDB GlyTouCan (G21290RB)
3	D (D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	E, F, G, H (A, B)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
5	I (B)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	1	Chemie (MPD)
6	J, K (A, B)	water	water		18.0	562	Chemie (HOH)

Sequence modifications

A, B: 27 - 301 (UniProt: Q8NBJ7)

PDB	External Database	Details
Arg 302	-	expression tag
Gly 303	-	expression tag
Ser 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	64549.8
Branched	Number of molecules	2
	Total formula weight	994.9
Non-Polymers*	Number of molecules	5
	Total formula weight	278.5
All*	Total formula weight	65823.2

*Water molecules are not included.