1XZZ
Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Inositol 1,4,5-trisphosphate receptor type 1 | polymer | 246 | 27421.2 | 1 | UniProt (P11881) Pfam (PF08709) | Mus musculus (house mouse) | Type 1 inositol 1,4,5- trisphosphate receptor, Type 1 InsP3 receptor, IP3 receptor isoform 1, InsP3R1, Inositol 1,4,5-trisphosphate-binding protein P400, Purkinje cell protein 1, Protein PCD-6 |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A: 2 - 223 (UniProt: P11881)
| PDB | External Database | Details |
|---|---|---|
| Met -14 | - | cloning artifact |
| Ala -13 | - | cloning artifact |
| Ser -12 | - | cloning artifact |
| Met -11 | - | cloning artifact |
| Thr -10 | - | cloning artifact |
| Gly -9 | - | cloning artifact |
| Gly -8 | - | cloning artifact |
| Gln -7 | - | cloning artifact |
| Gln -6 | - | cloning artifact |
| Met -5 | - | cloning artifact |
| Gly -4 | - | cloning artifact |
| Arg -3 | - | cloning artifact |
| Gly -2 | - | cloning artifact |
| Ser -1 | - | cloning artifact |
| Glu 0 | - | cloning artifact |
| Phe 1 | - | cloning artifact |
| Leu 224 | - | expression tag |
| Glu 225 | - | expression tag |
| His 226 | - | expression tag |
| His 227 | - | expression tag |
| His 228 | - | expression tag |
| His 229 | - | expression tag |
| His 230 | - | expression tag |
| His 231 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27421.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 27513.3 |
