1XXM
The modular architecture of protein-protein binding site
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Beta-lactamase TEM | polymer | 263 | 28805.9 | 2 | UniProt (P62593) Pfam (PF00144) Pfam (PF13354) In PDB | Escherichia coli | TEM-1; TEM-2; TEM-3; TEM-4; TEM-5; TEM-6; TEM-8/CAZ-2; TEM-16/CAZ-7; TEM-24/CAZ-6; IRT-4; Penicillinase |
2 | C, D | Beta-lactamase inhibitory protein | polymer | 165 | 17330.2 | 2 | UniProt (P35804) Pfam (PF07467) In PDB | Streptomyces clavuligerus | BLIP |
3 | C, D | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
4 | water | water | 18.0 | 417 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 288 (UniProt: P62593)
C, D: 1001 - 1165 (UniProt: P35804)
PDB | External Database | Details |
---|---|---|
Ile 84 | Val 82 | engineered mutation |
Ala 104 | Glu 102 | engineered mutation |
Ala 105 | Tyr 103 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ala 1074 | Lys 110 | engineered mutation |
Ala 1142 | Phe 178 | engineered mutation |
Ala 1143 | Tyr 179 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 92272.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 80.2 | |
All* | Total formula weight | 92352.3 |