1XTG
Crystal structure of NEUROTOXIN BONT/A complexed with Synaptosomal-associated protein 25
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NEUROTOXIN BONT/A | polymer | 424 | 48555.9 | 1 | GenBank (33321098) Pfam (PF01742) UniProt (by SIFTS) (P0DPI1) | Clostridium botulinum | |
| 2 | B (B) | Synaptosomal-associated protein 25 | polymer | 59 | 6739.6 | 1 | UniProt (P60880) | Homo sapiens (human) | SNAP-25, Super protein, SUP |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 372 | Chemie (HOH) |
Sequence modifications
A: 2 - 420 (GenBank: 33321098)
| PDB | External Database | Details |
|---|---|---|
| Gln 224 | Glu 224 | engineered mutation |
| Phe 366 | Tyr 366 | engineered mutation |
| Pro 421 | - | cloning artifact |
| Leu 422 | - | cloning artifact |
| Val 423 | - | cloning artifact |
| Pro 424 | - | cloning artifact |
| Arg 425 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55295.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 100.9 | |
| All* | Total formula weight | 55396.3 |
