1XQK
Effect of a Y265F Mutant on the Transamination Based Cycloserine Inactivation of Alanine Racemase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alanine racemase | polymer | 388 | 43679.1 | 2 | UniProt (P10724) Pfam (PF01168) Pfam (PF00842) | Geobacillus stearothermophilus | |
| 2 | C, D (A, B) | (5-HYDROXY-4-{[(3-HYDROXYISOXAZOL-4-YL)AMINO]METHYL}-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE | non-polymer | 331.2 | 2 | Chemie (PMH) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 476 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 382 (UniProt: P10724)
| PDB | External Database | Details |
|---|---|---|
| Kcx 129 | Lys 129 | modified residue |
| Phe 265 | Tyr 265 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 87358.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 662.4 | |
| All* | Total formula weight | 88020.6 |
